Article Text

Download PDFPDF
Dural spread from metastatic prostate cancer
  1. Niamh Peters1,
  2. Mohammed Zeeshan Zeeshan Zemeer1,
  3. Conor Waters2 and
  4. Richard Bambury1
  1. 1Medical Oncology, Cork University Hospital, Cork, Ireland
  2. 2Tallaght Hospital, Dublin, Dublin, Ireland
  1. Correspondence to Dr Niamh Peters; niamhpeters27{at}


A 59-year-old man with a known breast cancer type 1 gene mutation and a 2-year history of metastatic prostate cancer to bone and lymph nodes presented with a sudden onset of thunderclap headache, photophobia and a left sided facial droop. He was being treated at the time with the poly ADP ribose polymerase inhibitor Rucaparib. Of note, 6 weeks prior to this presentation, he had been diagnosed with malignant spinal cord compression at T3–T6, he underwent an emergency decompressive laminectomy and had received palliative postoperative radiotherapy. An urgent CT brain revealed dural metastases from his prostate cancer, with extensive oedema and midline shift. He underwent palliative whole brain radiotherapy but died 2 weeks later.

  • prostate cancer
  • neurooncology
  • radiotherapy

Statistics from


  • Contributors NP was the lead author on this paper and drafted the manuscript. CW provided assistance in the image descriptions and proof read/edited the paper. MZZZ and RB contributed to the paper by proof reading a number of drafts and suggesting edits.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.