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Primary thyroid leiomyosarcoma: a diagnostic and therapeutic challenge
  1. Mohammed Talha Bashir1,
  2. Tom Bradish2,
  3. Usman Rasul1 and
  4. Muhammad Shakeel2
  1. 1School of Medicine, University of Aberdeen, Aberdeen, UK
  2. 2Department of Otorhinolaryngology, Head and Neck surgery, Aberdeen Royal Infirmary, Aberdeen, UK
  1. Correspondence to Tom Bradish; tom.bradish{at}


Leiomyosarcoma is a malignant mesenchymal tumour of smooth muscle origin. It is extremely rare as a primary thyroid cancer with only 33 cases previously described in the literature. We present the case of a 69-year-old Caucasian man who presented with a 5-month history of left cervical lymphadenopathy and a suspicious mass in the left thyroid lobe on ultrasound scan. Left hemithyroidectomy confirmed the diagnosis of leiomyosarcoma. A review of current understanding and approaches to management of this rare condition are discussed.

  • ear
  • nose and throat/otolaryngology
  • thyroid disease
  • pathology

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  • Contributors MTB—primary author and data analysis. TB—secondary author, discussion, data analysis and publication correspondence. UR—assisted in data collection. MS—supervising consultant.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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