The syndrome of mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a rare mitochondrial disease with few documented cases in pregnancy. In this case report, we discuss the presentation and management of a 39-year-old grand multiparous lady with MELAS syndrome, which was diagnosed prior to her eighth pregnancy, discuss potential implications of the condition in pregnancy and summarise the current guidelines for the management of this rare condition.
- epilepsy and seizures
- genetic screening / counselling
- metabolic disorders
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DBN and MB are joint first authors.
Contributors MB and DBN drafted the initial article, analysed and interpreted the case and reviewed the literature. DTH and RP revised the manuscript critically. All authors listed on the manuscript have seen and approved the submitted letter and take full responsibility for the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
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