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Successful management of three cases of interstitial pregnancies with local instillation of potassium chloride: avoiding a potential cornuostomy
  1. Vineetha Shetty,
  2. Roopa Padavagodu Shivananda,
  3. Akhila Vasudeva and
  4. Jyothi Shetty
  1. Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India
  1. Correspondence to Dr Roopa Padavagodu Shivananda; roopasarun{at}


Here, we present three cases of women with interstitial pregnancy who were managed with local instillation of potassium chloride. These women were in their 20s–30s and presented in stable condition. Of them, two had a history of previous ectopic pregnancy. Interstitial pregnancy was diagnosed by transvaginal sonography which showed an empty uterine cavity with a gestational sac 1 cm away from the lateral edge of the uterine cavity, with <5 mm myometrium surrounding it in all planes. Two of the three cases failed to respond to methotrexate injection. Due to the presence of high-end ultrasound machine and technical expertise, local instillation of potassium chloride was offered as an alternative to surgical treatment, which is definitive, and all three patients had a successful outcome. One patient returned with pain in the abdomen, which required inpatient monitoring and was later diagnosed with urinary tract infection and was given appropriate antibiotics.

  • obstetrics
  • gynaecology and fertility
  • pregnancy

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  • Contributors VVS was involved in collection of data and writing the case report. RPS was involved in writing the case report and performed the procedure for case 3 and assisted in case 1. AV was involved in correction of the manuscript and performed the procedure for case 1 and assisted in case 3. JS was involved in correction of the manuscript and performed the procedure for case 2.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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