Article Text

Download PDFPDF
Gorham-Stout disease: interesting cause of pleural effusion
  1. Daniel Olea-Mendoza,
  2. Vittorio Romeo Terrigno,
  3. Ayobamidele Balogun and
  4. Colleen Caprio
  1. Internal Medicine, Cooper University Health Care, Camden, New Jersey, USA
  1. Correspondence to Dr Daniel Olea-Mendoza; olea-mendoza-daniel{at}cooperhealth.edu

Abstract

Gorham-Stout disease (GSD) is a rare disorder characterised by massive painless osteolysis due to lymphangiomatous tissue progression. GSD’s pathogenesis is still unclear, but osteoclasts' activation may play a role in its pathogenesis. There are multiple complications associated with GSD. One of the most severe and life-threatening complications is a chylothorax. Herein we discuss a case of a patient with a history of GSD who presented to the hospital with progressive dyspnoea secondary to a large left-sided pleural effusion, which was later confirmed to be a chylothorax. We will further discuss the current literature and treatment of chylothorax associated with GSD.

  • respiratory medicine
  • bronchopulmonary dysplasia
  • oncology
  • haematology (incl blood transfusion)
  • vascular surgery

Statistics from Altmetric.com

Footnotes

  • Contributors VT: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. DO: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. AB: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. CC: Responsible for proofreading and editing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.