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Abstract
Gorham-Stout disease (GSD) is a rare disorder characterised by massive painless osteolysis due to lymphangiomatous tissue progression. GSD’s pathogenesis is still unclear, but osteoclasts' activation may play a role in its pathogenesis. There are multiple complications associated with GSD. One of the most severe and life-threatening complications is a chylothorax. Herein we discuss a case of a patient with a history of GSD who presented to the hospital with progressive dyspnoea secondary to a large left-sided pleural effusion, which was later confirmed to be a chylothorax. We will further discuss the current literature and treatment of chylothorax associated with GSD.
- respiratory medicine
- bronchopulmonary dysplasia
- oncology
- haematology (incl blood transfusion)
- vascular surgery
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Footnotes
Contributors VT: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. DO: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. AB: Responsible for the planning and design of the case report. Also responsible for the written portion of the case report following the acquisition of data. CC: Responsible for proofreading and editing.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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