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Intravascular large B-cell lymphoma presenting with reticular telangiectasia on the trunk and panhypopituitarism: an autopsy case
  1. Midori Tokushima,
  2. Masaki Tago,
  3. Naoko E Katsuki and
  4. Shu-ichi Yamashita
  1. Department of General Medicine, Saga University Hospital, Saga, Japan
  1. Correspondence to Dr Masaki Tago; tagomas{at}


A 75-year-old woman developed redness and swelling on her truncal skin, spreading from the lower abdomen to left thigh, 2 months before being admitted to our hospital. She was urgently hospitalised because of her worsening respiratory condition. On admission, she had reticular telangiectasia, diffuse skin induration on the lower abdomen and panhypopituitarism. She was diagnosed with intravascular large B-cell lymphoma (IVLBCL) by the third random abdominal skin biopsy. After histopathological examination at autopsy, we made a final diagnosis of IVLBCL causing respiratory failure and panhypopituitarism. This is the rare case of IVLBCL-induced panhypopituitarism showing visible skin lesions.

  • endocrine system
  • dermatology
  • haematology (incl blood transfusion)
  • pathology

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  • MT and MT contributed equally.

  • Correction notice This article has been corrected since it was published Online First. The spelling of Department has been corrected in the affiliation.

  • Contributors MidoriT was involved in literature search and drafting. MasakiT was involved in concept, literature search and drafting. NEK was involved in literature search and drafting. SY was involved in concept and revision of article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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