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Silicone oil-associated orbital cellulitis with lipogranulomatous inflammation in the setting of HIV: a management challenge and clinicopathological correlation
  1. Khushboo Chauhan,
  2. Sunita Sabarwal,
  3. Deepak Soni and
  4. Samendra Karkhur
  1. Department of Ophthalmology, All India Institute of Medical Sciences Bhopal, Bhopal, Madhya Pradesh, India
  1. Correspondence to Dr Samendra Karkhur; karkhurs{at}


A 58-year-old Indian man presented with pain and redness of the left eye (OS) for one day. Patient had undergone silicone oil removal in OS for emulsified oil following vitrectomy and oil tamponade six months ago when he was diagnosed with retinal detachment in both eyes due to HIV retinopathy. Retinal detachment in the right eye (OD) was inoperable and had turned prephthisical at presentation, while his vision in OS was finger counting. Intraocular pressure in OD was 8 mm Hg and unrecordably elevated in OS. Extraocular movements were limited by periorbital oedema and proptosis. Slit-lamp examination revealed corneal haze, cells 2+/flare 1+ with pseudophakia, and attached retina. Histopathology showed lipogranulomatous inflammation, hitherto unreported in association with silicone oil. The index case posed a management challenge since his only functional eye had potentially been compromised by glaucoma and orbital cellulitis with compartment syndrome, against the backdrop of an immunocompromised status.

  • HIV / AIDS
  • glaucoma
  • eye
  • retina

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  • Contributors SK was involved in patient management. SK, KC, SS and DS contributed to the concept, design, literature search, and manuscript review and editing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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