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Case report
Diffuse encephalitic toxoplasmosis in HIV
  1. Jasmine Pearce1,
  2. Ray Sheridan2,
  3. Johnathan Shaw3 and
  4. Thomas Senior2
  1. 1Department of General Medicine, Royal Devon and Exeter Hospital, Exeter, UK
  2. 2Department of Healthcare for Older People, Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, UK
  3. 3Department of Sexual Health, North Devon District Hospital, Barnstaple, Devon, UK
  1. Correspondence to Jasmine Pearce; jasmine.pearce1{at}nhs.net

Abstract

This case demonstrates an atypical radiological presentation of cerebral toxoplasmosis in a 62-year-old HIV-positive patient. The diagnosis is discussed alongside MRI imaging, laboratory results and treatment. Central nervous system toxoplasmosis is typically associated with ring enhancing lesions on neuroimaging with contrast, but the radiology for this patient shows diffuse white matter changes and ependymal enhancement, which would normally suggest an alternative diagnosis.

  • infectious diseases
  • neurology
  • infection (neurology)

https://doi.org/10.1136/bcr-2020-237456

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    Footnotes

    • Contributors JP: design, data collection, data analysis and interpretation, drafting of the article, critical revision of the article, final approval of the version to be published. RS: conception of the article, data analysis and interpretation, critical revision of the article, final approval of the version to be published. JS: data analysis and interpretation, critical revision of the article, final approval of the version to be published. TS: drafting the article, final approval of the version to be published.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Next of kin consent obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.