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Demyelinating polyneuropathy associated with chronic inactive hepatitis B infection
  1. Mohamed A Babatin and
  2. Awatef AlJohani
  1. King Fahad Hospital Jeddah, Jeddah, Makkah, Saudi Arabia
  1. Correspondence to Dr Mohamed A Babatin; dmbabatin{at}


This is a case report of a 42-year-old female patient with chronic inactive hepatitis B virus (HBV) infection who presented with relapsing chronic inflammatory demyelinating polyneuropathy (CIDP). Her initial attack was of acute onset (ie, acute CIDP) resembling Guillain-Barré syndrome that responded well to intravenous immunoglobulin (IVIG) therapy. The second episode was chronic and refractory to IVIG. She was managed with plasma exchange, long-term corticosteroids, immunosuppressants and HBV antiviral therapy. She showed both clinical and electromyographic improvement, with no recurrence after 2 years of follow-up.

  • hepatitis B
  • neurological injury

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  • Contributors MAB is a hepatologist who saw the patient for consultation and managed and treated the patient for chronic hepatitis B and saw the patient at follow-up. AAJ is a neurologist who was the primary consultant who assessed the patient, got her admitted, managed and treated the patient from neurology point of few and saw the patient at follow-up.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.