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Case report
Topical interferon alpha-2b for a giant ocular surface squamous neoplasia: 7 years of follow-up after complete remission
  1. Virgilio Galvis1,2,
  2. Nathalia J Moreno2,1,
  3. Alejandro Tello2,1 and
  4. Néstor I Carreño2,1
  1. 1Ophthalmology, Centro Oftalmologico Virgilio Galvis, Floridablanca, Santander, Colombia
  2. 2Ophthalmology, Universidad Autonoma de Bucaramanga, Bucaramanga, Santander, Colombia
  1. Correspondence to Dr Alejandro Tello; alejandrotello{at}gmail.com

Abstract

A man with a history of blind eye due to trauma 22 years earlier consulted at 53 years of age with a large conjunctival neoplastic lesion, compromising almost the entire temporal limbus, and reaching a size of approximately 16 mm on its larger diameter, in the conjunctiva. Management was started with topical and subconjunctival chemotherapy (interferon alpha-2b) in order to perform immunoreduction, but a dramatic response with total disappearance of the lesion was observed. In the follow-up time period of more than 7 years, there were no signs of recurrence.

  • ophthalmology
  • cancer intervention
  • eye

https://doi.org/10.1136/bcr-2020-240994

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    Footnotes

    • Contributors VG was involved in the conception, planning, design, acquisition of data, analysis, interpretation of data and manuscript preparation and editing. NIC was involved in the conception, planning, design, acquisition of data, analysis, interpretation of data and manuscript preparation and editing. NJM was involved in the conception, planning, design, acquisition of data, analysis, interpretation of data and manuscript preparation and editing. AT was involved in the conception, planning, design, acquisition of data, analysis, interpretation of data and manuscript preparation and editing.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.