Article Text

Download PDFPDF
Simultaneous double laryngeal tumours: a diagnostic and therapeutic challenge
  1. Fergus Cooper1,
  2. Rafael Moleron2,
  3. Andrea Chapman3 and
  4. Muhammad Shakeel1
  1. 1Otolaryngology, Aberdeen Royal Infirmary, Aberdeen, UK
  2. 2Oncology, Aberdeen Royal Infirmary, Aberdeen, UK
  3. 3Pathology, Aberdeen Royal Infirmary, Aberdeen, UK
  1. Correspondence to Mr Fergus Cooper; fergus.cooper2{at}


Leiomyosarcomas are soft tissue tumours that rarely occur in the larynx. This case report describes the presentation and management of a 77-year-old man referred to the otolaryngology clinic with hoarseness who was found to have a large supraglottic leiomyosarcoma after panendoscopy and biopsies. He subsequently underwent laryngectomy for treatment of this tumour but, unexpectedly, the histological analysis of the laryngectomy specimen revealed a second primary tumour in the larynx—a squamous cell carcinoma (SCC). The patient had further treatment with neck radiotherapy. Three years after treatment, there are no signs of recurrence of either tumour. This case report discusses the very few similar cases of leiomyosarcoma coexisting with SCC in the larynx, collating the evidence surrounding the treatment of this rare presentation.

  • ear, nose and throat/otolaryngology
  • head and neck cancer
  • pathology
  • head and neck surgery
  • surgical oncology

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors FC is the lead author of this case report. FC led the literature search and gathered factual information and figures relating to the case. MS is the supervising author and was the lead ENT consultant involved with the patient’s care. MS contributed by revising and finalising the draft and collecting factual information and figures relating to the case. RM and AC contributed by revising and finalising the final draft and providing specialist input as the Oncologist and Pathologist involved in the patient’s case.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.