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Doxycycline Induced Severe Acute Pancreatitis: A Rare Finding To A Common Medication
  1. Neal Shah1,
  2. Anthony Razzano2 and
  3. James Grendell2
  1. 1Department of Internal Medicine, NYU Langone Hospital - Long Island, Mineola, New York, USA
  2. 2Department of Gastroenterology and Hepatology, NYU Langone Hospital - Long Island, Mineola, New York, USA
  1. Correspondence to Dr Neal Shah; neal.shah{at}


Doxycycline is a commonly prescribed antibiotic with growing evidence suggesting a possible linkage with drug-induced acute pancreatitis. We present an elderly female presenting with severe acute pancreatitis likely secondary to doxycycline therapy after thorough investigation. We reviewed the evidence linking doxycycline-inducing acute pancreatitis and signs and symptoms for severe disease. Early recognition and intervention are critical for positive patient outcomes.

  • gastrointestinal system
  • pancreatitis

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  • Contributors Supervised by JG. The patient was under the care of JG. The report was written by NS and AR.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.