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Panuveitis in a patient with active Crohn’s disease
  1. Tharini Senthamizh1,
  2. Kuppusamy Senthamizhselvan2,
  3. Niroj Kumar Sahoo1 and
  4. Subashini Kaliaperumal1
  1. 1Ophthalmology Department, Jawaharlal Institute of Post Graduate Medical Education and Research, Pondicherry, India
  2. 2Medical Gastroenterology, JIPMER, Puducherry, India
  1. Correspondence to Dr Kuppusamy Senthamizhselvan; senthamizh2909{at}gmail.com

Abstract

A 14-year-old girl presented to the ophthalmology clinic with progressive diminution of vision, redness, pain and photophobia in both eyes for the last 1 month. She had abdominal pain, diarrhoea and weight loss during that period. Ocular examination revealed features of anterior uveitis, vitritis and retinal vasculitis. In view of gastrointestinal symptoms, abdominal imaging was done, which showed multiple enhancing bowel wall thickening with skip lesions in the terminal ileum and ascending colon. Colonoscopy showed ulcers in the ascending colon, caecum and terminal ileum. Histopathology revealed microgranulomas in lamina propria and submucosal granulomas suggestive of Crohn’s disease. The patient was started on topical steroid eye drops and oral budesonide and mesalazine. Her vision improved after 3 weeks and bowel symptoms attained remission after 8 weeks, and at present, she is doing well.

  • Crohn's disease
  • anterior chamber
  • retina

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Footnotes

  • Contributors All authors certify that they have participated in the work to take public responsibility for the content, including participation in the concept, design, writing and revision of the manuscript. Each author certifies that this material has not been submitted or published in any other publication. TS was responsible for planning and preparation of the manuscript. KS was responsible for the design of the manuscript, and for revising the manuscript critically. NKS was responsible for the acquisition of data. SK was responsible for revising the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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