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Unusual cause of a painless soft tissue mass of the scalp: a rare presentation of primary intracranial neuroendocrine neoplasm
  1. Susruta Manivannan1,
  2. Feras Sharouf2,3,
  3. George Lammie2 and
  4. Paul Leach4
  1. 1Neurosurgery, Southampton University Hospitals NHS Trust, Southampton, UK
  2. 2School of Medicine, Cardiff University, Cardiff, UK
  3. 3Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK
  4. 4Department of Neurosurgery, University Hospital of Wales, Cardiff University, Cardiff, UK
  1. Correspondence to Dr Feras Sharouf; sharouffh{at}cardiff.ac.uk

Abstract

Incidental soft tissue lumps in the scalp are a common presenting complaint in clinical practice. However, they may signify more sinister underlying pathologies. Our report examines a 63-year-old man presenting with impaired co-ordination in his left hand following a 3-month history of a painless left retroauricular scalp lump. MRI revealed a large left occipital soft tissue mass eroding through the underlying skull with infiltration into the underlying cerebellum and temporal lobe. Open biopsy confirmed a diagnosis of high-grade intracranial neuroendocrine tumour (NET). At approximately 5 months following successful tumour resection and adjuvant chemotherapy, he developed tumour recurrence and was subsequently palliated, and died at 1 year post diagnosis. Herein, we review other cases of primary intracranial NET, clinical findings, histopathological features and prognosis.

  • neurosurgery
  • endocrine cancer

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Footnotes

  • Contributors SM: Concept and first draft. FS: Radiology images and review of manuscript. GL: Pathology report and review of manuscript. PL: Concept and review of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.