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Severe neonatal autoimmune thrombocytopenia secondary to maternal Evans syndrome
  1. Shafini Beryl,
  2. Benjamin Jeyanth Ross,
  3. Mintoo Tergestina and
  4. Manish Kumar
  1. Department of Neonatology, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
  1. Correspondence to Dr Mintoo Tergestina; tergestina{at}gmail.com

Abstract

Evans syndrome is a rare and chronic autoimmune disease seen in both paediatric and adult age groups. We present a case of severe thrombocytopenia in a neonate born to a mother with Evans syndrome who showed no response to intravenous immunoglobulin therapy initially and improved after treatment with methylprednisolone.

  • neonatal intensive care
  • haematology (incl blood transfusion)
  • materno-fetal medicine
  • neonatal and paediatric intensive care

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Footnotes

  • Contributors All authors were involved in management. SB and MT wrote the manuscript. BJR and MK reviewed the manuscript. All four authors are guarantors of the paper. All are in agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.