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Case report
Self-limiting severe neutropenia in a patient with COVID-19
  1. Ram Singh,
  2. Brajesh Kumar Ratre,
  3. Prashant Sirohiya and
  4. Sushma Bhatnagar
  1. Onco-Anaesthesia and Palliative Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, India
  1. Correspondence to Dr Ram Singh; dr.ram2001{at}gmail.com

Abstract

Neutropenia is a rare haematological complication of COVID-19 infection in immunocompetent patients. There is sparse literature on neutropenia in patients with COVID-19, except a few case reports. We encountered a similar case in an intensive care unit that developed severe neutropenia on day 24 of illness. Neutropenia resolved spontaneously on 4th day of its appearance. The patient was isolated and kept under close observation, antibiotics were upgraded and strict asepsis was maintained. Thus, we observed in a patient with no comorbidities and uncomplicated neutropenia that strict measures to prevent infection may suffice and the undue risk of hematopoietic therapy can be avoided. An expert opinion should always be sought in such cases as the presence of complications may require an aggressive approach.

  • COVID-19
  • haematology (incl blood transfusion)
  • intensive care

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2021-247057

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    Footnotes

    • Twitter @sirohiyap

    • Contributors RS: Planning, manuscript writing, reporting the work and case management and also acts as the guarantor. BKR: Editing, final approval of manuscript and case management. PS: Final approval and case management. SB: Critical review and Final approval

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.