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Anaesthetic challenges in the spine surgery of a young Asian man with lumbar amyloidosis
  1. Jabraan Jamil1,
  2. Chong Yan Tay2,
  3. Chin Pei Bong3 and
  4. Tat Boon Yeap4
  1. 1Anaesthesia and Intensive Care Unit, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia
  2. 2Department of Paediatrics, Melaka General Hospital, Melaka, Malaysia
  3. 3Department of Orthopaedics, Hospital Queen Elizabeth, Kota Kinabalu, Sabah, Malaysia
  4. 4Department of Anaesthesiology and Intensive Care, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia
  1. Correspondence to Dr Tat Boon Yeap; boontat{at}


Primary amyloidosis is a rare systemic disorder often associated with multiple organ dysfunction. The most common form, light chain amyloidosis, has an estimated age-adjusted incidence of 5.1–12.8 cases per million person-years. Spine involvement is extremely uncommon. We present the case of a young Asian man with newly diagnosed amyloidosis involving the lumbar spine among multiple organs with a pathological vertebral fracture that required urgent spine surgery. We believe this is the first reported case to discuss the perianaesthetic challenges in the management of lumbar spine amyloidosis.

  • anaesthesia
  • orthopaedics
  • orthopaedic and trauma surgery

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  • Contributors TBY, CPB and JJ are the clinicians managing the patient. They co-authored this manuscript as well as were involved in data collection. CYT is the co author of this manuscript together with other clinicians mentioned.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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