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Recurrent ataxia and dysarthria in myelin oligodendrocyte glycoprotein antibody-associated disorder
  1. Uddalak Chakraborty1,
  2. Shrestha Ghosh2,
  3. Amlan Kusum Datta1 and
  4. Atanu Chandra2
  1. 1Neurology, Institute of Postgraduate Medical Education and Research Bangur Institute of Neurology, Kolkata, West Bengal, India
  2. 2Internal Medicine, RG Kar Medical College and Hospital, Kolkata, West Bengal, India
  1. Correspondence to Dr Atanu Chandra; chandraatanu123{at}


The spectrum of central nervous system demyelinating disorders is vast and heterogeneous and, often, with overlapping clinical presentations. Misdiagnosis might occur in some cases with serious therapeutic repercussions. However, introduction of several new biomarkers such as aquaporin-4 IgG and myelin oligodendrocyte glycoprotein IgG has made distinction between diseases such as multiple sclerosis and myelin oligodendrocyte glycoprotein antibody-associated disorder easier. Here, we report a case of a 15-year-old male patient with subacute multifocal neurological presentation without encephalopathy, eventually diagnosed as myelin oligodendrocyte glycoprotein antibody-associated disorder.

  • neurology
  • neuroimaging
  • immunology

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  • Contributors UC and SG prepared the manuscript with adequate planning and execution; they also collected data regarding the patient. UC and AKD were the direct care givers to the patient, who managed the case actively and collected relevant data on investigations with equal contributorship. AC helped in detailed supervision, final output and the review of literature regarding the manuscript. All authors are in agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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