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Acute-onset chronic inflammatory demyelinating polyneuropathy after COVID-19 infection and subsequent ChAdOx1 nCoV-19 vaccination
  1. Vinit Suri1,
  2. Shishir Pandey1,
  3. Jyoti Singh1 and
  4. Amarnath Jena2
  1. 1Neurology, Indraprastha Apollo Hospital, New Delhi, Delhi, India
  2. 2Nuclear Medicine, Indraprastha Apollo Hospital, New Delhi, Delhi, India
  1. Correspondence to Dr Vinit Suri; vinitsuri{at}


SARS-COV-2 predominantly results in a respiratory illness. However, it has also been associated with a wide range of neurological disorders including a broad range of immune neuropathies. These immune neuropathies associated with SARS-COV2 infection include Guillain-Barré syndrome (GBS), recurrent GBS and exacerbation of pre-existing chronic inflammatory demyelinating polyneuropathy (CIDP). We describe a case with acute-onset CIDP presenting with three relapses of demyelinating polyradiculoneuropathy, the third relapse occurring in the 8 week of illness following a previous COVID-19 infection and a recent COVID-19 vaccination with ChAdOx1 nCoV-19 and high COVID-19 antibody level. In our knowledge, this is the ever reported case of acute-onset CIDP associated with COVID-19 vaccine and high COVID-19 antibody level.

  • COVID-19
  • vaccination/immunisation
  • peripheral nerve disease

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  • Contributors VS drafted the article, JS and SP helped in research work and conceptualisation. AJ reported the MRI and PET images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.