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Spectrum of presentation in primary anorectal malignant melanoma and its management
  1. Barun Kumar Singh1,
  2. Samrat Ray1,
  3. Shashi Dhawan2 and
  4. Samiran Nundy1
  1. 1Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, India
  2. 2Pathology/Histopathology Unit, Sir Ganga Ram Hospital, New Delhi, India
  1. Correspondence to Dr Samrat Ray; samrat.ray2711{at}


The article presents a series of four patients with primary anorectal melanoma presenting to our institute between 2016 and 2021. The primary objective of the series is to give an overview of the variable presentation of this rare entity from a high-volume colorectal tertiary care centre in a developing country. The patients ranged in age from 55 to 73 years and were mostly women (except one). The clinical presentation varied from bleeding per rectum to tenesmus and mucus in stools, overlapping with those of inflammatory bowel disease and primary anorectal adenocarcinoma. All patients were treated with surgery (laparoscopic or open), ranging from local excision to abdominoperineal resection. All our patients had a good outcome after surgery with no mortality at 30 or 90 days after surgery. The article aims to present a comprehensive overview of the various options of management with evidence from the surgical literature.

  • skin cancer
  • radiotherapy
  • colon cancer
  • cancer
  • surgical oncology

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  • Contributors BKS prepared the first draft of the manuscript and collected all the relevant literature and data. SR was the chief supervisor of the project who edited the manuscript and supervised the project. SD was the pathologist involved in the project, and provided the images and inputs from the pathology team. SN was the chief supervisor involved in the final approval and editing of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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