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Too young to break? A rare case of premenopausal osteoporosis
  1. Iqra Patoli1,
  2. Mian Zeeshan Munir1 and
  3. Sameerah Rehmani2
  1. 1Internal Medicine, St Mary's Hospital, Waterbury, Connecticut, USA
  2. 2Bayview Physicians Group, Suffolk, Virginia, USA
  1. Correspondence to Dr Mian Zeeshan Munir; mianmunir809{at}gmail.com

Abstract

We present a case of a 29-year-old female with fragility fracture of the ninth thoracic vertebrae with a z-score of −3.3 of the lumbosacral spine. She was worked up for secondary causes of osteoporosis, all of which was unrevealing except for a low vitamin D level which was repleted. She had genetic profile done, which revealed low-density lipoprotein receptor-related 5 mutation which was thought to the cause of premature osteoporosis. This report highlights a rare case of osteoporosis in a premenopausal female and challenges associated with premenopausal osteoporosis.

  • musculoskeletal and joint disorders
  • osteoporosis
  • genetics

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Footnotes

  • Contributors IP ran point on the case, and MZM helped with literature review and data acquisition. Editing and data review were done by SR.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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