We present a case of a 29-year-old female with fragility fracture of the ninth thoracic vertebrae with a z-score of −3.3 of the lumbosacral spine. She was worked up for secondary causes of osteoporosis, all of which was unrevealing except for a low vitamin D level which was repleted. She had genetic profile done, which revealed low-density lipoprotein receptor-related 5 mutation which was thought to the cause of premature osteoporosis. This report highlights a rare case of osteoporosis in a premenopausal female and challenges associated with premenopausal osteoporosis.
- musculoskeletal and joint disorders
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Contributors IP ran point on the case, and MZM helped with literature review and data acquisition. Editing and data review were done by SR.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
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