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Non-allergic benign infantile proctocolitis: a neglected nosographic entity
  1. Mariannita Gelsomino1,
  2. Dario Sinatti1 and
  3. Stefano Miceli Sopo2
  1. 1Post-Graduate School of Pediatrics, Department of Life Sciences and Public Health, Policlinico Gemelli Universitary Foundation IRCCS, Catholic University of Sacre Hearth, Roma, Lazio, Italy
  2. 2Pediatric Allergy Unit, Pediatrics Section, Department of Life Sciences and Public Health, Policlinico Gemelli Universitary Foundation IRCCS, Catholic University of Sacre Hearth, Roma, Italy
  1. Correspondence to Professor Stefano Miceli Sopo; stefano.micelisopo{at}unicatt.it

Abstract

The presence of rectal bleeding in the first months of life is very often diagnosed as food protein-induced allergic proctocolitis (FPIAP). The symptoms typically start in infancy, and most cases resolve by age 12 months. Infants with FPIAP usually present bloody stools mixed with mucus, with or without reduced stool consistency. Most affected infants are generally healthy-appearing. We used the story of an infant with rectal bleeding as a reminder that there is also the possibility of a form of benign non-allergic proctocolitis that is not usually included in the differential diagnosis. In the absence of warning signs and in case of infant well-being, it should be the first clinical entity to suspect. Therefore, we suggest we should wait at least 2 months before starting to eliminate cow milk or other foods from the diet.

  • GI bleeding
  • endoscopy
  • infant health

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Footnotes

  • Contributors SMS conceived design of the study. MG drafted the article. DS and MG acquired the data and researched the scientific literature, analysed and commented on it. All authors revised the article and gave final approval of the version to be published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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