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Treatment of benzodiazepine withdrawal syndrome in a severe traumatic brain injury patient
  1. Ming Kai Teah1,
  2. Guan Keng Chan1,
  3. Melvin Teck Fui Wong1 and
  4. Tat Boon Yeap2
  1. 1Department of Anaesthesia and Intensive Care Unit, Hospital Queen Elizabeth, Kota Kinabalu, Malaysia
  2. 2Medicine Based Disciplines Department, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Malaysia
  1. Correspondence to Dr Tat Boon Yeap; boontat{at}


Prolonged exposure to benzodiazepines (BDZ) may contribute towards physical dependence, which is manifested by iatrogenic Benzodiazepine Withdrawal Syndrome (BWS), a condition often underdiagnosed. Current evidence recommends precluding BDZ infusion as sedation in the intensive care unit to avoid possible withdrawal and delirium issues. Administration of dexmedetomidine should be considered to facilitate weaning in patients with BWS.

  • adult intensive care
  • mechanical ventilation
  • intensive care

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  • Contributors MKT was involved in the management of patient and writing of manuscript. GKC was involved in the management of patient. MTFW was involved in the management of patient. TBY was involved in the manuscript writing and editing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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