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Case report
CA 125 and TB
  1. Mirae Park1,2,
  2. Ranju Dhawan3,4,
  3. Elizabeth Whittaker5 and
  4. Onn Min Kon2,6
  1. 1Imperial Clinical Respiratory Research Unit, Imperial College Healthcare NHS Trust, London, UK
  2. 2Faculty of Medicine, National Heart and Lung Institute, London, UK
  3. 3Department of Imaging and Radiology, Imperial College Healthcare NHS Trust, London, UK
  4. 4Hybrid Imaging & Therapy Unit, Wellington Hospital, London, UK
  5. 5Paediatric Infectious Diseases and Immunology, Imperial College Healthcare NHS Trust, London, UK
  6. 6Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK
  1. Correspondence to Dr Mirae Park; m.park{at}imperial.ac.uk

Abstract

We present two unusual presentations of extrapulmonary tuberculosis (EPTB) and more specifically intra-abdominal tuberculosis (TB). These cases were initially suspicious for ovarian cancer, presenting with non-specific symptoms, ultrasound-confirmed ascites and elevated cancer antigen 125 tumour marker (CA 125). However, in both cases chest imaging demonstrated enlarged mediastinal nodes amenable to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which confirmed the diagnosis of TB. Both cases were successfully treated with quadruple TB therapy.

  • respiratory medicine
  • tuberculosis

https://doi.org/10.1136/bcr-2020-238199

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    Footnotes

    • Contributors MP, RD, EW and OMK all contributed for the draft, revision and final edits to this case report.

    • Funding This study was funded by NIHR Imperial Biomedical Research Centre (P68495).

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.