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Ductal and lobular carcinoma in situ arising within an enlarging biopsy proven fibroadenoma
  1. Yara Z Feliciano1,
  2. Rochelle Freire2,
  3. Jose Net1 and
  4. Monica Yepes1
  1. 1Radiology Department, University of Miami Miller School of Medicine, Miami, Florida, USA
  2. 2Pathology Department, University of Miami Miller School of Medicine, Miami, Florida, USA
  1. Correspondence to Dr Yara Z Feliciano; yxf238{at}miami.edu

Abstract

The diagnosis via core needle biopsy of concurrent ductal carcinoma in situ and lobular carcinoma in situ within an enlarging previously biopsied benign fibroadenoma in women in their 40s is rare. Several case reports have described the occurrence of malignant changes within fibroadenomas, usually as an incidental finding following excision, and few reports have documented the transition of a fibroadenoma to malignancy. The current case report emphasises the importance of re-biopsying enlarging fibroadenomas, even with otherwise maintained benign appearing features on imaging, in women in their 40s, in order to exclude the possibility of malignancy.

  • radiology
  • breast surgery
  • breast cancer

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Footnotes

  • Contributors YF: Conception and design, acquisition of data, radiology interpretation, literature review, drafting the article and critical revision. RF: Pathology interpretation, literature review, drafting the article and critical revision. JN: Radiology interpretation, literature review, drafting the article and critical revision. MMY: Radiology interpretation, literature review, drafting the article and critical revision.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.