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Acute generalised exanthematous pustulosis: an unusual cause of carpal tunnel syndrome
  1. Xuxin Lim1 and
  2. Kai Yuen Wong2
  1. 1Paediatric Surgery, KK Women's and Children's Hospital, Singapore
  2. 2Plastic and Reconstructive Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
  1. Correspondence to Kai Yuen Wong; kaiyuen.wong{at}


A 65-year-old man presented with generalised erythematous pustular rash following an insect bite. He was initially treated with antibiotics for presumed cellulitis. He subsequently developed bilateral carpal tunnel syndrome. Skin biopsy confirmed a diagnosis of acute generalised exanthematous pustulosis, which resolved with oral prednisolone. He also had steroid injections for his bilateral carpal tunnel syndrome and this recovered uneventfully. Clinical presentation, histological assessment and EuroSCAR criteria were key to the diagnosis and management of this case.

  • dermatology
  • general practice / family medicine
  • orthopaedics
  • surgery
  • plastic and reconstructive surgery

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  • Contributors XL and KYW both made substantial contributions to the drafting and final approval of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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