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Case report
Management of recurrent central giant cell granuloma of mandible using intralesional corticosteroid with long-term follow-up
  1. Kumar Nilesh1,
  2. Anuj Dadhich2 and
  3. Rahul Patil3
  1. 1Oral & Maxillofacial Surgery, Krishna Institute of Medical Sciences Deemed University, Karad, India
  2. 2Department of Oral and Maxillofacial Surgery, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
  3. 3Oral Pathology, Pravara Institute of Medical Sciences, Loni, Maharashtra, India
  1. Correspondence to Dr Kumar Nilesh; drkumarnilesh{at}


Central giant cell granuloma (CGCG) is an expansile osteolytic lesion of the jawbone. Conventional treatment of CGCG is surgical and vary from simple curettage to more aggressive resection of the jaw. However, surgical management is associated with drawbacks including requirement of hospitalisation and general anaesthesia, damage to vital anatomic structures and continuity defect of the mandible requiring reconstruction surgery. Use of intralesional injections of corticosteroid for the management of CGCG have been inconsistently used as an alternative non-surgical method of management of CGCG with varying success. While the use of such conservative modality over ablative surgery can significantly reduce postoperative morbidity, follow-up of such cases for a long period is important to study the possible recurrence. This paper reports successful treatment of a recurrent CGCG of posterior mandible by intralesional administration of triamcinolone acetonide in a 27-year old female patient, with long-term follow-up of 10 years.

  • dentistry and oral medicine
  • oral and maxillofacial surgery

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  • Contributors KN and AD were involved in patient management. KN and RP were involved in manuscript writing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.