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New disease
Case report
COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman
  1. Abigail Anness and
  2. Farah Siddiqui
  1. Department of Obstetrics and Gynaecology, University Hospitals of Leicester NHS Trust, Leicester, UK
  1. Correspondence to Dr Abigail Anness; abigailanness{at}gmail.com

Abstract

The COVID-19 outbreak has spread across the globe at an alarming rate. As the pandemic escalates, experience of COVID-19 in pregnant women is accumulating. We present a case of COVID-19 pneumonia in a 28-week pregnant woman with a known low lying placenta. The patient had deranged liver function tests at presentation, along with elevated bile acids. We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. The low lying placenta in this patient meant that we had to carefully consider the application of recommendations for thromboprophylaxis in pregnant COVID-19 patients. With supportive management, this patient improved enough to be discharged, and has gone on to deliver a healthy neonate at term.

  • obstetrics and gynaecology
  • pregnancy
  • liver disease
  • infectious diseases

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2020-237007

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    Footnotes

    • Contributors Patient was under the care of FS. Report was written by AA. Supervised by FS.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.