You are here

Article Text

Article menu
Download PDFPDF
Rare disease
Case report
Congenital dysfibrinogenaemia presented with preterm premature rupture of the membranes and vaginal bleeding
  1. Zaker I Schwabkey1,
  2. Farrell C Sheehan1,
  3. Courtney Bellomo1,2 and
  4. Mihir Raval1,2
  1. 1Department of Internal Medicine, Albany Medical College, Albany, New York, USA
  2. 2New York Oncology Hematology PC, Albany, New York, USA
  1. Correspondence to Dr Zaker I Schwabkey; schwabkey{at}gmail.com

Abstract

A 26-year-old woman was found to have congenital dysfibrinogenaemia after presenting to our hospital with premature rupture of the membranes and vaginal bleeding. Given the absence of clear guidelines for the management of pregnancy complicated by dysfibrinogenaemia, we followed expert consensus that exists among published works, with some modifications. This case was managed by a multidisciplinary team of obstetrics-gynaecology, haematology and paediatric haematology. Here we review how the patient presented, the investigations that led to the diagnosis and the treatment options.

  • pregnancy
  • genetics
  • haematology (incl blood transfusion)
  • malignant and benign haematology

https://doi.org/10.1136/bcr-2020-235961

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    • Contributors ZIS and FCS gathered the information and wrote the initial draft. CB and MR took care of the patient. MR revised the manuscript and mentored our work.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.