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Case report
Rheumatoid arthritis in a patient with cystic fibrosis: challenging treatment options
  1. Kelly Lynn Delaney-Nelson,
  2. Sheena Marie Henry and
  3. Chokkalingam Siva
  1. Department of Internal Medicine, Division of Rheumatology, University of Missouri Health System, Columbia, Missouri, USA
  1. Correspondence to Dr Kelly Lynn Delaney-Nelson; kldelaney33{at}


A 26-year-old Caucasian male patient with a history of cystic fibrosis presented with a 6-month history of diffuse joint pain and swelling. He was found to have active synovitis in bilateral wrists and proximal interphalangeal joints of the hands on physical examination. He was diagnosed with seropositive rheumatoid arthritis since he had positive anti-cyclic citrullinated peptide antibodies and erosions on hand and foot X-rays. The patient has responded well to abatacept which may have less infection risk compared with other biological therapies.

  • rheumatoid arthritis
  • cystic fibrosis
  • biological agents

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  • KLD-N and SMH are joint first authors.

  • Contributors KLD-N and SMH contributed equally to this paper (development, image procurement and editing). CS contributed to the planning and editing of this paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.