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Case report
Incidental finding of monoclonal B-cell lymphocytosis in the mandible
  1. Pritam Daniel Sundaresan1,2 and
  2. Magdalen Foo1,2
  1. 1Maxillofacial & Dental Surgery, Fiona Stanley Hospital, Perth, Western Australia, Australia
  2. 2Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Western Australia, Australia
  1. Correspondence to Dr Pritam Daniel Sundaresan; Daniel.Sundaresan{at}


A 78-year-old man was referred to the Special Needs Dentistry Clinic for review prior to beginning bisphosphonate treatment as part of the management for his metastatic prostate cancer given the increased risk of medication-related osteonecrosis of the jaws in this patient cohort. Imaging revealed a well-defined radiolucency in the mandible that was closely associated with a non-vital anterior tooth. The lesion was asymptomatic. Incisional biopsy revealed a low grade B cell lymphoproliferation compatible with a monoclonal B-cell lymphocytosis (MBL). The patient was subsequently referred to haematology as MBL may develop into chronic lymphocytic leukaemia.

  • dentistry and oral medicine
  • haematology (incl blood transfusion)
  • prostate cancer

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  • Contributors PDS and MF were both involved in the clinical management of this patient, as well as preparation of this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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