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Case report
Viral and bacterial coinfection of the respiratory tract in a 10-month-old child
  1. Sandhya Govindarajan1 and
  2. Saha Bivan2
  1. 1Speciality Registrar, Department of Paediatrics and Neonates, North Manchester General Hospital, Manchester, UK
  2. 2Consultant, Department of Paediatrics and Neonates, North Manchester General Hospital, Manchester, England, UK
  1. Correspondence to Dr Sandhya Govindarajan; ggsan28{at}


A 10-month-old child, immunised appropriately for age, presented with a history of cough, vomiting, diarrhoea, increased work of breathing and eye redness for 1 week. She was treated for suspected bronchiolitis with supportive oxygen and hypertonic saline nebulisation. In view of continuing fever spikes and persistent oxygen requirement, she was evaluated further. Her inflammatory markers were raised, blood film showed neutrophils left shift with toxic granulations and chest X-ray was suggestive of the right upper lobe segmental atelectasis suggestive of a bacterial infection. Her nasopharyngeal aspirate for multiplex tandem PCR was positive for adenovirus, respiratory syncytial virus and Bordetella species. She was treated with oral clarithromycin for 5 days which improved her symptoms. She was discharged with further follow-up. Coinfection with bacteria or atypical bacteria in children with acute respiratory tract infection is common and this coinfection can induce serious illness.

  • bronchiolitos
  • vaccination/immunisation

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  • Contributors SG: contributed in the design of work, acquisition of data, drafting report and literature review and accountable for all aspects of the work, including patient care. SB: involved in direct clinical care of the patient, final approval of the version and accountable for accuracy and integrity of work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.