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Unusual presentation of more common disease/injury
Case report
Cervicovaginal cellular angiofibroma
  1. Sarah Van Mulders1,
  2. Ellen Faes1,
  3. Glenn Broeckx2 and
  4. Yves Jacquemyn1
  1. 1Department of Obstetrics and Gynecology, University Hospital Antwerp, Edegem, Antwerp, Belgium
  2. 2Department of Pathology, University Hospital Antwerp, Edegem, Antwerp, Belgium
  1. Correspondence to Professor Yves Jacquemyn; yves.jacquemyn{at}uza.be

Abstract

Cellular angiofibroma is a rare type of benign mesenchymal tumour that arises mostly in middle-aged women. It needs to be distinguished from other neoplasms and has a predilection for the vulvovaginal region. To our knowledge, this is the first case of a cervical cellular angiofibroma. A 34-year-old nulligravid woman was referred with a large mass bulging in the fornix posterior. Ultrasound scanning and MRI showed a large solid mass projecting in the pouch of Douglas. Laparoscopic surgical excision was performed. Histopathological examination showed a well-demarcated, unencapsulated tumour, consisting of short fascicles of spindle cells in-between thick-walled medium-sized vessels. On immunohistochemistry, there was strong reactivity with antibodies against CD34 and oestrogen receptor. Angiofibromas are benign mesenchymal tumours mostly occurring in middle-aged women. They can cause abnormal swelling and uterine bleeding and need to be distinguished from other (malignant) neoplasms.

  • obstetrics and gynaecology
  • pathology
http://creativecommons.org/licenses/by-nc/4.0/

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

https://doi.org/10.1136/bcr-2020-235241

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    Footnotes

    • Contributors The patient was referred to our tertiary centre after the diagnosis of a large vaginal mass. YJ, head of the department of Obstetrics and Gynaecology, was the gynaecologist to whom this patient was referred. He planned elective surgery to have the mass removed and was in charge of the follow-up of the patient. SVM, registrar in Obstetrics and Gynaecology in the same centre, got involved after the surgery was already performed and the definitive diagnosis was made. Interested by the case she performed literature research and decided to write a case report. Supported by and under supervision of YJ and EF, consultant Obstetrics and Gynaecology in the same centre, she wrote down her gynaecological findings. GB is anatomopathologist and was consulted in writing the case report. He wrote the histopathological conclusions and revised the case report as well.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.