An unusual presentation of sclerosing angiomatoid nodular transformation in a 42-year-old man who was admitted with jaundice, deranged liver function tests and subsequently diagnosed with acute hepatitis C infection in the context of recent intravenous drug use. During his admission, he had an ultrasound of the abdomen followed by a CT thorax, abdomen and pelvis which showed splenomegaly and a large splenic lower pole mass that was hypoechoic and concerning for lymphoma. A bone marrow biopsy showed no evidence of lymphoma and an ultrasound-guided biopsy of the splenic mass suggested unusual features with vascular proliferation, either neoplastic or reactive, with no evidence of lymphoma or high-grade sarcoma. Given the concern for malignancy, an open splenectomy was required to determine the nature of the lesion with histologic findings consistent with a non-neoplastic benign vascular lesion favouring sclerosing angiomatoid nodular transformation.
- liver disease
- hepatitis C
- general surgery
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Contributors CSB: collection of data and images, writing and reporting of initial draft and subsequent drafts with corrections and obtaining patient consent. AW: literature review, guidance/planning and conduct of paper, editing and proof reading of final draft, editing of images and submission of paper. MM: general supervision and planning, proof reading of drafts, guidance and input from theatre, operation details and guidance for acquisition of patient consent. HPR: head of department, general supervision and planning, final review of article and conception/initial idea to write report.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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