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Case report
Index case of synovial metastasis in a patient with transitional cell carcinoma of the bladder
  1. Ruhaid Khurram1,
  2. Aqsa Khurram2 and
  3. Khurram Chaudhary1
  1. 1Department of Cellular Pathology, Royal Free London NHS Foundation Trust, London, UK
  2. 2Barts and The London School of Medicine and Dentistry, London, UK
  1. Correspondence to Dr Ruhaid Khurram; ruhaidk{at}


Synovial metastasis is a rare presentation with only a few reported cases in the published literature. A majority of cases of malignant synovitis have a primary lung or colorectal origin. It carries a poor prognosis with an average survival of approximately 5 months from diagnosis. The treatment options are limited to palliative approaches, which highlight the aggressive nature of the presentation as well as the necessity for early recognition. We report an index case of synovial metastasis of the knee joint in a patient with progressive transitional cell carcinoma of the bladder and review the literature with respect to synovial metastasis.

  • haematuria
  • pathology
  • urological cancer

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  • Contributors All authors have equally contributed to the case report which includes conceptualisation, literature review, writing, editing and reviewing prior to publication. RK conceptualised the case report, performed literature review and was involved in writing and reviewing the case report. AK was involved in literature review, writing and editing the case report. KC was involved in writing, editing, reviewing and providing expert opinion.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.