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Case report
Optic nerve invasion of non-juxtapapillary uveal melanoma: a rare occurrence
  1. Abhimanyu Sharma1,
  2. Dilip K Mishra2 and
  3. Swathi Kaliki1
  1. 1Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, India
  2. 2Ophthalmic Pathology Service, LV Prasad Eye Institute, Hyderabad, India
  1. Correspondence to Dr Swathi Kaliki; kalikiswathi{at}


A 44-year-old man presented with complaints of pain and discomfort in his left eye (OS). On examination, he had bare perception of light in OS and had a diffuse pigmented mass lesion in the nasal quadrant of the bulbar conjunctiva, associated with neovascularisation of the iris and iridocyclitis, with no fundus view. Intraocular pressure OS was 40 mm Hg. B-scan ultrasonography OS revealed an intraocular mass with thickened sclerochoroidal complex. A clinical diagnosis of OS ciliochoroidal melanoma with extraocular extension was made. He underwent OS extended enucleation with implant. Histopathological examination confirmed the diagnosis of ciliochoroidal melanoma with tumour extension into the optic nerve posteriorly and the extrascleral tissues anteriorly. There was no evidence of systemic metastasis. Even in a case of non-juxtapapillary uveal melanoma, poor vision and high intraocular pressure are clinical indicators of optic nerve tumour invasion.

  • ophthalmology
  • macula
  • pathology

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  • Contributors AS is responsible for collection of data and drafting the manuscript. DKM is responsible for pathology reporting and revision of the manuscript. SK is responsible for managing the patient, and formulation and revision of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.