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Case report
Invasive cervical adenocarcinoma arising from extension of recurrent vulval Paget’s disease
  1. Liesel Elisabeth Hardy1,2,
  2. Lachlan Baxter1,
  3. King Wan1 and
  4. Chloe Ayres1
  1. 1Gynaecological Oncology, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia
  2. 2Pathology, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia
  1. Correspondence to Dr Liesel Elisabeth Hardy; lieselhardy{at}


An 83-year-old woman with a long-standing history of both invasive and vulval extramammary Paget’s disease (EMPD) was referred to a tertiary gynaecological oncology service for suspicion of contiguous extension to the vagina and cervix. Vaginal biopsies confirmed EMPD; however, a loop excision of the cervix demonstrated invasive adenocarcinoma arising from Paget’s disease. The patient subsequently underwent laparoscopic radical hysterectomy, bilateral salpingo-oophorectomy and radical upper vaginectomy, confirming FIGO stage 1B1 cervical adenocarcinoma. She was recommended but declined to have adjuvant pelvic external beam radiotherapy. To our knowledge this is the second case of invasive cervical adenocarcinoma arising from vulval Paget’s disease in the literature.

  • cervical cancer
  • oncology
  • surgery
  • gynaecological cancer

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  • Contributors LEH is the primary author and wrote the case. LB, KW and CA assisted with editing the case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.