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Case report
Ureaplasma urealyticum infection presenting as pyelonephritis and perinephric abscess in an immunocompromised patient
  1. Alexander Ngoo1,
  2. Jared Eisemann2,
  3. Admire Matsika3 and
  4. David Winkle1
  1. 1Department of Urology, Mater Hospital Brisbane, Brisbane, Queensland, Australia
  2. 2Department of Infectious Diseases, Mater Hospital Brisbane, Brisbane, Queensland, Australia
  3. 3Department of Anatomical Pathology, Mater Hospital Brisbane, Brisbane, Queensland, Australia
  1. Correspondence to Dr Alexander Ngoo; ALEXANDERGA-ONN.NGOO{at}HEALTH.QLD.GOV.AU


We report a case of an immunosuppressed 67-year-old woman who presented with fever of unknown origin. Further investigation revealed multiple left renal and perinephric abscesses. These were managed with percutaneous drainage and broad-spectrum antibiotics; however, no clinical improvement resulted. No organism was identifiable on standard microscopy and culture of all drain, blood and urine samples taken. Left nephrectomy with right urinary diversion was performed for sepsis management and to protect the patient’s right kidney. Eventually, Ureaplasma species’ RNA was detected in the patient’s drain fluid using PCR and 16S ribosomal RNA gene sequencing. The patient was treated successfully with targeted antibiotic therapy and underwent extensive rehabilitation following this. Histopathology of the nephrectomy specimen suggested xanthogranulomatous pyelonephritis.

  • urology
  • infectious diseases
  • renal medicine

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  • Contributors AN was involved in the planning, conception and design, and was the primary author who wrote the manuscript for this submission. JE and DW were involved in the planning and conception, and were contributing authors to the manuscript in the writing process. AM was involved in planning, conception and provision of histopathological slides for this publication. Some input was also placed into the manuscript particularly in regards to terminology regarding histopathology.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.