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Case report
Romiplostim for management of refractory immune thrombocytopenic purpura in the immediate postpartum period

Abstract

We present a case of a pregnant woman with chronic immune thrombocytopenic purpura and chronic hypertension who developed pre-eclampsia with severe features warranting delivery. Her overall clinical picture and liver enzymes improved in the immediate postpartum period, however, aggressively progressing thrombocytopenia posed a diagnostic dilemma to the interdisciplinary care team. After failing to respond to first-line therapies including high-dose corticosteroids and intravenous immunoglobulin, she was successfully managed with a trial of the thrombopoietin receptor agonist, Romiplostim.

  • obstetrics, gynaecology and fertility
  • haematology (incl blood transfusion)
  • pregnancy

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