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Case report
Multidrug-resistant tuberculosis of lumbosacral spine producing extensive destruction with lumbosacral kyphosis
  1. Tushar Rathod,
  2. Ashwin Sathe and
  3. Shivaprasad Kolur
  1. Department of Orthopedics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India
  1. Correspondence to Dr Ashwin Sathe; ashwinsathe{at}


It is uncommon to get lumbosacral junction deformity due to tuberculosis. Lumbosacral junction alignment is of paramount importance in maintaining global sagittal balance. In this case report, we present a case of a 42-year-old woman with multidrug-resistant tuberculosis of lumbosacral spine with complete destruction of L3, L4 and L5 vertebra with partial destruction of L2 and S1 vertebra leading to significant shortening and lumbosacral kyphosis. The patient had severe axial low back pain, inability to sleep in supine position due to deformity and difficulty in walking due to loss of spinal alignment. The patient was treated with 6 weeks of antituberculous drugs followed by all posterior decompression with instrumentation from D10 to S2 with a reconstruction of anterior vertebral bodies with the help of an expandable cage. Antituberculous treatment was continued for 18 months. At present, the patient is asymptomatic with no neurological deficit and has completed 3.5 years of regular follow-up.

  • bone and joint infections
  • orthopaedics

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  • Contributors TR is the first author who has operated upon the patient, maintained the records and edited the manuscript. AS, the second and corresponding author, has contributed in managing the records and preparing and editing the manuscript. SK contributed in editing the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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