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Case report
Eight-and-a-half syndrome: video evidence and updated literature review
  1. Marco A Cárdenas-Rodríguez,
  2. Sergio A Castillo-Torres,
  3. Beatriz Chávez-Luévanos and
  4. Laura De León-Flores
  1. Servicio de Neurología, Hospital Universitario "Dr José E. González", Universidad Autónoma de Nuevo León, Monterrey, NL, Mexico
  1. Correspondence to Dr Sergio A Castillo-Torres; sergio.castillotr{at}


The eight-and-a-half syndrome (EHS)—defined by the combination of a seventh cranial nerve palsy and an ipsilateral one-and-a-half syndrome—is a rare brainstem syndrome, which localises to the caudal tegmental region of the pons. We present a case of the EHS secondary to an inflammatory lesion on a previously healthy 26-year-old woman, with a literature review emphasising the relevance of aetiological assessment.

  • brain stem / cerebellum
  • cranial nerves
  • neuroimaging

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  • Contributors MAC-R and SAC-T contributed to the article conception and design, as well as drafting of the manuscript. MAC-R obtained consent from the patient. BC-L and LDL-F contributed with the examination of the patient and significance of clinical findings, and the critical review of the manuscript for intellectually relevant content. All authors agreed on the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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