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Case report
Lipotransfer provides effective soft tissue replacement for acquired partial lipodystrophy
  1. Faith Hyun Kyung Jeon1,
  2. Michelle Griffin1,2,
  3. Carole Frosdick2 and
  4. Peter Edward Michael Butler1,2
  1. 1Division of Surgery & Interventional Science, University College London, London, UK
  2. 2Department of Plastic and Reconstructive Surgery, Royal Free London NHS Foundation Trust, London, UK
  1. Correspondence to Dr Faith Hyun Kyung Jeon; h.jeon{at}


We present a 48-year-old female patient who presented with features consistent with acquired partial lipodystrophy (APL) also known as ‘Barraquer-Simons syndrome’. It is a rare disease characterised by a gradual and progressive onset of lipoatrophy limited to the face, neck, upper limbs, thorax and abdomen and sparing the lower extremities. The resultant physical appearance can have significant psychosocial sequelae, further compounded by misdiagnosis and delay in recognition and management. Treatment is aimed at surgical correction of soft tissue destruction. Autologous fat transfer is an established plastic and reconstructive procedure that is safe and minimally invasive and can be used to reconstruct a variety of soft tissue defects and has shown to be an effective treatment modality in patients with APL.

  • plastic and reconstructive surgery
  • breast surgery

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  • Contributors All authors have seen and approved the final manuscript. All authors have made substantial contributions to all of the following: (1) the conception and design of the study (FHKJ and MG), or acquisition of data (FHKJ and CF), or analysis and interpretation of data (FHKJ), (2) drafting the article or revising it critically for important intellectual content (FHKJ and MG) and (3) final approval of the version to be submitted (MG and PEMB). The manuscript, including related data, table and images, has not been previously published and that the manuscript is not under consideration elsewhere.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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