Article Text

Download PDFPDF
Case report
Extra-skeletal Ewing’s sarcoma of the frontal sinus: a rare disorder in pediatric age


Paediatric sinonasal tumours comprise numerous aetiologies. Ewing’s sarcoma (ES) consists of a malignancy of neuroectodermal origin. This type of sarcoma affects mainly children and adolescents and can assume the skeletal or extra-skeletal form. Primary ES of head and neck is extremely rare, accounting for only 4%–9% of all cases. So far, as much as we know, only a few cases of sinonasal ES have been reported in literature. The authors present a case of a previous healthy 12-year-old girl who presented with a rapidly growing and expansive frontal mass and unilateral nasal obstruction. Immunohistochemical, molecular and cytogenetic analysis of the lesion showed diffuse expression of CD56 and CD99 on tumour cells and a translocation involving chromosome 22q12, confirming ES diagnosis.

  • ear, nose and throat/otolaryngology
  • paediatrics (drugs and medicines)
  • chemotherapy
  • head and neck cancer
  • paediatric oncology
View Full Text

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.