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Case report
Cardiac calcified amorphous tumour associated with multiple myeloma
  1. Tetsuo Yamanaka1,
  2. Toru Fukatsu1,
  3. Tomoya Uchimuro2 and
  4. Shuichiro Takanashi2
  1. 1Tokyo Teishin Hospital, Chiyoda-ku, Japan
  2. 2Kawasaki Saiwai Hospital, Kawasaki-shi, Japan
  1. Correspondence to Dr Tetsuo Yamanaka; yamanaka_tetsuo{at}


We report an 86-year-old woman who was diagnosed with multiple myeloma (MM) and was receiving chemotherapy since the age of 82. A high echoic mass attached to the mitral valve was observed on transthoracic echocardiography 4 years after the treatment. The possibility of malignancy could not be ruled out, and hence, the mass was excised surgically. Pathologically, most of the mass consisted of calcified lesion without tumour tissue, and these findings were not inconsistent with calcified amorphous tumour (CAT). This case suggests that CAT may be associated with MM and has been reported after a thorough literature review.

  • cardiovascular medicine
  • haematology (incl blood transfusion)

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  • Contributors TY wrote the initial draft of the manuscript. TY, TF, TU and ST contributed to analysis and interpretation of data, and assisted in the preparation of the manuscript. All other authors have contributed to data collection and interpretation, and critically reviewed the manuscript. The final version of the manuscript was approved by all authors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.