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Case report
Type B lactic acidosis: a rare oncological emergency
  1. Qiuying Selina Liu1,
  2. Farzana Harji1,2,
  3. Anna Jones1,3 and
  4. Amy C Tarnower1,3
  1. 1Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
  2. 2Internnal Medicine, New Mexico VA Health Care System, Albuquerque, New Mexico, USA
  3. 3Internal Medicine, University of New Mexico Cancer Research and Treatment Center, Albuquerque, New Mexico, USA
  1. Correspondence to Dr Qiuying Selina Liu; qiliu{at}


Type B lactic acidosis is a rare metabolic complication of malignancy, more commonly in haematological malignancies. Due to the lack of formal prospective trials, treatment of lactic acidosis associated with malignancy is based on case reports. Given the poor prognosis, early recognition of type B lactic acidosis and prompt treatment are crucial. We report the first case of type B lactic acidosis in metastatic melanoma, followed by a brief literature review on the proposed pathophysiology and treatment.

  • skin cancer
  • palliative care
  • chemotherapy

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  • Contributors QSL wrote the first draft. AJ, ACT and FH revised and finalised the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Next of kin consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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