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Case report
Intractable pleural effusion in Kaposi sarcoma following antiretroviral therapy in a Caucasian female infected with HIV
  1. Pattraporn Tajarernmuang1,
  2. Pierre-Olivier Fiset2,
  3. Jean-Pierre Routy3,4 and
  4. Stéphane Beaudoin5
  1. 1 Medicine, Division of Pulmonary, Critical Care, and Allergy, Chiang Mai University, Chiang Mai, Thailand
  2. 2 Department of Pathology, McGill University Health Centre, Montreal, Québec, Canada
  3. 3 Research Institute, McGill University Health Centre, Montreal, Québec, Canada
  4. 4 Division of Haematology, McGill University Health Centre, Montreal, Québec, Canada
  5. 5 Division of Respirology, McGill University Health Centre, Montreal, Québec, Canada
  1. Correspondence to Dr Stéphane Beaudoin; stephane.beaudoin{at}mcgill.ca

Abstract

We report the case of a 57-year-old Caucasian woman with AIDS-related disseminated Kaposi sarcoma (KS) characterised by the combination of several unusual features. The chylous nature of the pleural effusions, the documented parietal pleural involvement at thoracoscopy and the marked clinical worsening through an immune reconstitution syndrome following antiretroviral therapy initiation represent several rare situations that occurred in the same female patient. In addition, the use of indwelling pleural catheters for dyspnoea palliation also represents a rare therapeutic intervention. This case is a reminder of the possibility of AIDS-related pleural KS, now uncommon in the era of antiretroviral therapy.

  • HIV / AIDS
  • palliative procedures
  • malignant disease and immunosuppression
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Footnotes

  • Contributors PT contributed to the planning of the manuscript, reviewed the patient file, performed the literature review, and wrote the first and final draft of the manuscript. P-OF participated in the planning of the manuscript, reviewed the pathology aspects of the case, provided the images and their interpretation, reviewed the drafts and approved the final version of the manuscript. J-PR participated in the planning of the manuscript, reviewed the haematological course of the patient, contributed to the literature review, reviewed the first draft and approved the final draft of the manuscript. SB planned the manuscript, contributed to file review and literature review, reviewed the manuscript drafts and approved the final version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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