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Case report
Concurrent Guillain-Barré syndrome and myositis complicating dengue fever
  1. Manisha Gulia,
  2. Preeti Dalal,
  3. Monica Gupta and
  4. Daljinderjit Kaur
  1. Department of General Medicine, Government Medical College and Hospital, Chandigarh, India
  1. Correspondence to Professor Monica Gupta; monicamanish2001{at}


Dengue is an arboviral infection that classically presents with fever, headache, joint pain, skin flush and morbilliform rashes. Neurological manifestations are well recognised but their exact incidence is unknown. Though myalgias are common in dengue virus infection, myositis and/or elevated serum creatine kinase is an uncommon complication. Guillain-Barré syndrome is another rare neurological manifestation associated with dengue fever. Here, we report the case of a 21-year-old man with serologically confirmed dengue fever presenting with severe myalgia, bilateral lower and upper limb weakness with raised creatine kinase, MRI suggestive of myositis and myonecrosis and nerve conduction velocity showing bilateral lower limb and axillary sensory motor neuropathy. He was managed conservatively and made an uneventful recovery.

  • infectious diseases
  • infection (neurology)
  • muscle disease
  • peripheral nerve disease

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  • Contributors All the authors have provided substantial contributions in the clinical management of the case and literature review on the topic in question. MG and PD have drafted the manuscript, and MG and DK have revised it critically for important intellectual content. All the authors have read the final version and approved it. All the authors agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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