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Case report
Recurrent metastatic primary inflammatory myofibroblast tumour of the gallbladder following pancreaticoduodenectomy
  1. Roi Anteby1,2,
  2. Brianne J Sullivan1,
  3. Malary Mani3 and
  4. Benjamin Golas1
  1. 1 Division of Surgical Oncology, Mount Sinai Hospital, New York, NY, USA
  2. 2 Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
  3. 3 Department of Pathology, Mount Sinai Hospital, New York, NY, USA
  1. Correspondence to Mr Roi Anteby; roianteby{at}


Inflammatory myofibroblast tumour (IMT) is an uncommon soft tissue tumour with an unpredictable clinical course: mostly benign, occasionally locally aggressive and rarely capable of metastasis. Diagnosed mainly in the mesentery, omentum, retroperitoneum, pelvis and lungs, IMT is extremely rare as a primary gallbladder tumour. Despite improved radiographical capabilities, differentiating the tumour from other more common causes of gallbladder neoplasms necessitates histopathological and immunohistochemistry tests. Once diagnosed, malignant potential should be taken into consideration, striving for an en bloc R0 resection and postoperative long-term follow-up with routine ancillary imaging. The authors present the case of a recurrent primary IMT of the gallbladder, after two surgical treatments, including a pancreaticoduodenectomy. Now 3 years after initial diagnoses the patient is asymptomatic, but has developed local and distant metastases and is being treated with systemic corticosteroid.

  • surgical oncology
  • pancreas and biliary tract
  • cancer intervention
  • gastrointestinal surgery
  • pathology
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  • Contributors RA, BJS and BG were responsible for planning the case and conceived the original idea. RA, BJS, MM and BG wrote the manuscript. BG helped supervise and conduct the project. The design of the manuscript was done by RA and BJS. Data were acquired by RA and BJS, and images were acquired and prepared by RA, BJS and MM. Data interpretation was performed by RA, BJS, MM and BG. BJS, MM and BG were directly involved in the treatment of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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