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Case report
Behçet’s disease presenting as recurrent oral aphthosis in a 9-year-old boy from Greece
  1. George Panos1,2,
  2. Loukas Kakoullis3,4,
  3. Stylianos Louppides3 and
  4. Andreas Emmanuil5
  1. 1Infectious Diseases Section, University General Hospital of Patras, Patras, Achaia, Greece
  2. 2Internal Medicine, University Cyprus School of Medicine, Nicosia, Cyprus
  3. 3Internal Medicine, Nicosia General Hospital, University of Cyprus Medical School, Nicosia, Cyprus
  4. 4Respiratory Medicine, University General Hospital of Patras, Patras, Greece
  5. 5Biochemical Laboratory, University General Hospital of Patras, Patras, Greece
  1. Correspondence to Professor George Panos; george.panos.frcp{at}


We report a case of Behçet’s disease in a 9-year-old boy from Greece, presenting with a history of recurrent ulceration of the oral cavity. Following inspection of the oral cavity, which revealed lesions on both the upper and lower labial mucosa, as well as a large ulcer on the apex of the tongue, the diagnosis of Behçet’s disease was immediately suspected. The diagnosis was confirmed using the International Criteria for Behçet’s Disease. Nevertheless, as multiple diseases can cause recurrent oral aphthosis, an extensive differential diagnosis was made, and pertinent tests were undertaken to exclude other causes of oral ulceration. The approach to a patient with Behçet’s disease, as well as its various clinical presentations and complications, is discussed.

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  • Contributors GP evaluated and diagnosed the patient described in this case report, instructed LK and SL on how to draft the manuscript and reviewed the manuscript. LK and SL examined the patient and drafted the manuscript. AE evaluated the patient, obtained the signed consent form and contributed significantly to the drafting of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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