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Giant left atrial septal pouch stained during trans-septal puncture
  1. Hiroshi Kuwaki1,
  2. Hajime Yamashita1,
  3. Yuki Shimada1 and
  4. Keiji Ujino2
  1. 1Cardiology, Baba Memorial Hospital, Sakai, Japan
  2. 2Cardiology, Tominaga Hospital, Osaka, Japan
  1. Correspondence to Dr Hiroshi Kuwaki; h.kuwaki{at}gmail.com

https://doi.org/10.1136/bcr-2020-240128

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    Description

    A 66-year-old man with old cerebral infarction and paroxysmal atrial fibrillation (AF) was admitted to our hospital for dyspnoea on exertion. A 12-lead ECG showed AF. Transoesophageal echocardiography (TEE) revealed no thrombus in the left atrium, and a prominent left atrial septal pouch (LASP) was visualised (figure 1). In addition, TEE showed negative bubble study with and without Valsalva manoeuvre (figure 2). Then, we performed circumferential pulmonary vein isolation for the treatment of AF. During the trans-septal access with standard Brockenbrough method, it was noted that the contrast agent injected through the tip of the needle filled the LASP cavity (video 1).

    Figure 1
    Figure 1

    Mid-oesophageal bicaval view showed the giant membrane of LASP spreading to interatrial septum. LA, left atrium; LASP, left atrial septal pouch; RA, right atrium.

    Figure 2
    Figure 2

    The microbubbles produced by an agitated saline with a provocative test could not detect patent foramen ovale. LA, left atrium; LASP, left atrial septal pouch; RA, right atrium.

    Video 1

    The embryological aetiology of LASP is incomplete fusion of the septum primum and septum secundum during the closure of foramen ovale. Fusion limited to the caudal portion of the zone of overlap leads to creation of the LASP.1 Mazur et al reported the presence of LASP in 40.8% of 294 healthy adult hearts in postmortem examination. The mean volume of the LASP was 0.31±0.11 mL, which makes up only 13.6%±9.4% (range: 3.1%–44.9%) of the appendage, and the average depth of the LASP was 8.4±5.1 mm.2 Hence, the LASP is a relatively small structure. However, in our case, the depth of LASP with a giant flap spreading to LA cavity (the white arrows in figure 1) was 30 mm. As the LASP cavity is surrounded by transverse muscle, it was difficult to insert catheters from the septal wall and isolate the right pulmonary veins. We consider that (1) the presence of LASP may also cause blood stasis in the LASP cavity, increasing the risk of blood clots formation and potentially lead to ischaemic stroke,3 (2) the muscle layers of LASP may become an arrhythmogenic substrate responsible for triggering AF4 and (3) the flap of LASP restricts the motion of the catheters as a result of difficulty of AF ablation.

    Learning points

    • The left atrial septal pouch (LASP) cavity may increase the risk of blood clots formation and potentially lead to ischaemic stroke.

    • The muscle layers of LASP may become an arrhyrthmogenic substrate for triggering atrial fibrillation (AF).

    • The flap of LASP restricts the motion of catheters as a results of difficulty of AF ablation.

    References

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    Footnotes

    • Contributors HY: participated in the writing or technical editing of the manuscript. YS: participating investigator; KU: provided study patient. HK: prepare, create this work.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally-peer reviewed.